Honestly, I think Peace Walker broaches the subject of generative AI more directly than MGS2. The whole question plaguing Snake is whether or not this machine is a person he loved that's gone, or just a hunk of codes that can replicate her without actually being her. Not to mention Coldman letting AI handle something as severe as nuclear deterrence.
That said, MGS2's theme of disinformation and how humans only hear the truths they wanna hear and can be conditioned into believing any truth some bad actors decide on feels more relevant than ever.
That said, MGS2's theme of disinformation and how humans only hear the truths they wanna hear and can be conditioned into believing any truth some bad actors decide on feels more relevant than ever.